Hypoxic Chambers for Research
Hypoxic chambers play a critical role in cell culture research. These processes require strict control of O2, CO2, humidity, and temperature throughout the entire experimental workflow.
The principle of a hypoxic chamber is to create a fully controlled working atmosphere. Cells can be introduced, observed, and manipulated directly within the chamber without interrupting the incubation conditions required for the experiment.
By maintaining stable environmental parameters, hypoxic chambers allow researchers to reproduce precise physiological conditions, ensuring reliable and repeatable experimental outcomes.
Controlled and Anaerobic Atmospheres
Specific atmospheric conditions — particularly oxygen control and sometimes humidity regulation — are essential in many fields such as:
- microbiome science
- medical research
- cell and gene therapy
- advanced therapy medicinal products (ATMPs)
- nanoparticle-based anticancer therapies
In the pharmaceutical industry
Excess oxygen levels and high humidity can degrade certain sensitive compounds. Conversely, hygroscopic substances may require a controlled humidified environment to remain stable.
In scientific and industrial pharmaceutical applications
The development of new processes or experimental protocols often requires a strict anaerobic atmosphere to ensure accurate results.
In microbiology
Traditional nitrogen purge techniques remain empirical, limited, and inconsistent in terms of performance.
Jacomex has developed a more efficient oxygen removal technology using a gas purification system with a regenerable catalyst integrated into the purification unit. This ensures stable, long-term anaerobic conditions with improved reliability.
Key Features of Jacomex Hypoxic and Anaerobic Chambers
Jacomex hypoxic chambers offer several major advantages:
- integrated multi-range trace O2 analyzer with HMI interface
- guaranteed oxygen levels below 1 ppm O2
- long-term atmosphere stability
- fully reproducible experimental conditions
- minimal gas consumption and reduced maintenance costs
- regenerable catalyst lasting several years (alternative to palladium systems)
- full compatibility with Jacomex aseptic isolators and laminar flow systems
- accelerated process validation for research and production
Jacomex designs and manufactures several containment solutions. Three main models are available:
The PureEvo
The PureEvo is a premium glove box model equipped with an autonomous purification system capable of maintaining oxygen levels below 1 ppm O2.
Designed for anaerobic cell development, it provides optimal safety and can be configured with a wide range of optional equipment depending on the intended application.
A version with a highly cleanable working volume is also available. The PureEvo can be delivered fully customized or in standard dimensions.
The PureMod
The PureMod is a modular glove box system equipped with an autonomous purification unit maintaining oxygen levels below 1 ppm O2.
This model is recommended for experimental work in:
- biochemistry
- microbiology
- molecular biology
- protein engineering
- industrial research applications
Its modular architecture makes it particularly suitable for laboratories requiring flexibility and scalability.
The PureSmart
The PureSmart is a fully standardized glove box solution that integrates an autonomous purification unit maintaining oxygen levels below 1 ppm O2 while delivering high performance.
This model is designed for reproducing controlled or protective atmospheres, making it ideal for:
- academic research
- standard laboratory applications requiring controlled atmospheres
Jacomex, Your Expert Partner
For more than 75 years, Jacomex has been a global reference in the design and manufacture of containment enclosures and controlled atmosphere systems.
All Jacomex shielding enclosures and containment solutions are designed and manufactured in Lyon, France, and installed in more than 60 countries across industries including:
- nuclear
- scientific research
- pharmaceutical manufacturing
- medical technologies
- additive manufacturing
- energy
- organic electronics
Jacomex operates in full compliance with the regulatory standards specific to each application sector and continuously invests in research and development to provide equipment with:
- enhanced performance
- improved ergonomics
- increased process safety
If you would like to learn more about our hypoxic chambers or discuss your project, contact our experts.